Yes. A damaged or out-of-balance driveshaft, worn joints, or a faulty support bearing can cause vibration. Driveshaft operating angles and installation problems can also affect how smoothly the assembly turns.
However, vibration does not prove that the driveshaft is faulty. Tires, wheels, axles, and other components can create similar sensations.
Tell Certified Transmission in Bellevue which speeds bring on the vibration and whether it changes when you release the accelerator. That information helps narrow the inspection without replacing parts based on a symptom alone.